Sterile headspace aeration with variable volumetric flow rates prevents cross and external contaminations. Integrated exhaust gas cooling minimizes occuring evaporation losses. Easy realizable high throughput experiments due to parallelization allow highly reduced development time for new production processes. Miniaturization into the low milliliter-scale (8 - 15 ml) guarantees enormous material and cost savings.
Simple scaling-up of the results into production scale due to precisely defined engineering parameters and the comparable power and oxygen input to well-established stirred tank reactors. The bioREACTOR can be operated as standalone or fully automated by integration into a pipetting robot (Tecan). |